RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus

EGF induces the translocation of EGF receptor (EGFR) from the cell surface to the nucleus where EGFR activates gene transcription through its binding to an AT-rich sequence (ATRS) of the target gene promoter. However, how EGFR, without a DNA-binding domain, can bind to the gene promoter is unclear....

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שמור ב:
מידע ביבליוגרפי
Main Authors: Huo, Longfei, Wang, Ying-Nai, Xia, Weiya, Hsu, Sheng-Chieh, Lai, Chien-Chen, Li, Long-Yuan, Chang, Wei-Chao, Wang, Yan, Hsu, Ming-Chuan, Yu, Yung-Luen, Huang, Tzu-Hsuan, Ding, Qingqing, Chen, Chung-Hsuan, Tsai, Chang-Hai, Hung, Mien-Chie
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2010
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941329/
https://ncbi.nlm.nih.gov/pubmed/20802156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000743107
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