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Loss of c-Met Disrupts Gene Expression Program Required for G2/M Progression during Liver Regeneration in Mice
BACKGROUND: Previous work has established that HGF/c-Met signaling plays a pivotal role in regulating the onset of S phase following partial hepatectomy (PH). In this study, we used Met(fl/fl);Alb-Cre(+/−) conditional knockout mice to determine the effects of c-Met dysfunction in hepatocytes on kine...
में बचाया:
| मुख्य लेखकों: | , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Public Library of Science
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940888/ https://ncbi.nlm.nih.gov/pubmed/20862286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012739 |
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