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The disruption of the rod-derived cone viability gene leads to photoreceptor dysfunction and susceptibility to oxidative stress
Rod-derived Cone Viability Factor is a thioredoxin-like protein which has therapeutic potential for rod-cone dystrophies such as retinitis pigmentosa (RP). Cone loss in rodent models of RP is effectively reduced by RdCVF treatment. Here we investigate the physiological role of RdCVF in the retina by...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933397/ https://ncbi.nlm.nih.gov/pubmed/20139892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.2 |
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