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Expression of Rod-Derived Cone Viability Factor: Dual Role of CRX in Regulating Promoter Activity and Cell-Type Specificity

BACKGROUND: RdCVF and RdCVF2, encoded by the nucleoredoxin-like genes NXNL1 and NXNL2, are trophic factors with therapeutic potential that are involved in cone photoreceptor survival. Studying how their expression is regulated in the retina has implications for understanding both their activity and...

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Main Authors: Lambard, Sophie, Reichman, Sacha, Berlinicke, Cynthia, Niepon, Marie-Laure, Goureau, Olivier, Sahel, José-Alain, Léveillard, Thierry, Zack, Donald J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951342/
https://ncbi.nlm.nih.gov/pubmed/20949100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013075
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