Rod-derived Cone Viability Factor-2 is a novel bifunctional-thioredoxin-like protein with therapeutic potential

BACKGROUND: Cone degeneration is the hallmark of the inherited retinal disease retinitis pigmentosa. We have previously identified a trophic factor "Rod-derived Cone Viability Factor (RdCVF) that is secreted by rods and promote cone viability in a mouse model of the disease. RESULTS: Here we re...

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Detalhes bibliográficos
Main Authors: Chalmel, Frédéric, Léveillard, Thierry, Jaillard, Céline, Lardenois, Aurélie, Berdugo, Naomi, Morel, Emmanuelle, Koehl, Patrice, Lambrou, George, Holmgren, Arne, Sahel, José A, Poch, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central|1 2007
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064930/
https://ncbi.nlm.nih.gov/pubmed/17764561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-74
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