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Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration
Alternative splicing of nucleoredoxin-like 1 (Nxnl1) results in 2 isoforms of the rod-derived cone viability factor. The truncated form (RdCVF) is a thioredoxin-like protein secreted by rods that promotes cone survival, while the full-length isoform (RdCVFL), which contains a thioredoxin fold, is in...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4382269/ https://ncbi.nlm.nih.gov/pubmed/25415434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65654 |
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