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Functional Cone Rescue by RdCVF Protein in a Dominant Model of Retinitis Pigmentosa

In retinitis pigmentosa (RP), a majority of causative mutations affect genes solely expressed in rods; however, cone degeneration inevitably follows rod cell loss. Following transplantation and in vitro studies, we demonstrated the role of photoreceptor cell paracrine interactions and identified a R...

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Detalhes bibliográficos
Main Authors: Yang, Ying, Mohand-Said, Saddek, Danan, Aude, Simonutti, Manuel, Fontaine, Valérie, Clerin, Emmanuelle, Picaud, Serge, Léveillard, Thierry, Sahel, José-Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835133/
https://ncbi.nlm.nih.gov/pubmed/19277021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.28
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