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Clinical Trial Designs for Predictive Biomarker Validation: One Size Does Not Fit All

Traditionally, anatomic staging systems have been used to provide predictions of individual patient outcome and, to a lesser extent, guide the choice of treatment in cancer patients. With targeted therapies, biomarkers have the potential for providing added value through an integrated approach to pr...

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Autori principali: Mandrekar, Sumithra J., Sargent, Daniel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931323/
https://ncbi.nlm.nih.gov/pubmed/19384694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543400902802458
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