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Clinical trial designs incorporating predictive biomarkers()

Development of oncologic therapies has traditionally been performed in a sequence of clinical trials intended to assess safety (phase I), preliminary efficacy (phase II), and improvement over the standard of care (phase III) in homogeneous (in terms of tumor type and disease stage) patient populatio...

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Detalhes bibliográficos
Publicado no:Cancer Treat Rev
Main Authors: Renfro, Lindsay A., Mallick, Himel, An, Ming-Wen, Sargent, Daniel J., Mandrekar, Sumithra J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737867/
https://ncbi.nlm.nih.gov/pubmed/26827695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2015.12.008
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