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Clinical trial designs incorporating predictive biomarkers()

Development of oncologic therapies has traditionally been performed in a sequence of clinical trials intended to assess safety (phase I), preliminary efficacy (phase II), and improvement over the standard of care (phase III) in homogeneous (in terms of tumor type and disease stage) patient populatio...

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Bibliografiske detaljer
Udgivet i:Cancer Treat Rev
Main Authors: Renfro, Lindsay A., Mallick, Himel, An, Ming-Wen, Sargent, Daniel J., Mandrekar, Sumithra J.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737867/
https://ncbi.nlm.nih.gov/pubmed/26827695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2015.12.008
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