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Clinical trial designs incorporating predictive biomarkers()

Development of oncologic therapies has traditionally been performed in a sequence of clinical trials intended to assess safety (phase I), preliminary efficacy (phase II), and improvement over the standard of care (phase III) in homogeneous (in terms of tumor type and disease stage) patient populatio...

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Détails bibliographiques
Publié dans:Cancer Treat Rev
Auteurs principaux: Renfro, Lindsay A., Mallick, Himel, An, Ming-Wen, Sargent, Daniel J., Mandrekar, Sumithra J.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737867/
https://ncbi.nlm.nih.gov/pubmed/26827695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2015.12.008
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