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Design of clinical trials for biomarker research in oncology

The developmental pathway from discovery to clinical practice for biomarkers and biomarker-directed therapies is complex. While several issues need careful consideration, two critical issues that surround the validation of biomarkers are the choice of clinical trial design (which is based on the str...

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Autori principali: Mandrekar, Sumithra J, Sargent, Daniel J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290127/
https://ncbi.nlm.nih.gov/pubmed/22389760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/CLI.11.152
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