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Design of clinical trials for biomarker research in oncology

The developmental pathway from discovery to clinical practice for biomarkers and biomarker-directed therapies is complex. While several issues need careful consideration, two critical issues that surround the validation of biomarkers are the choice of clinical trial design (which is based on the str...

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Detalhes bibliográficos
Main Authors: Mandrekar, Sumithra J, Sargent, Daniel J
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290127/
https://ncbi.nlm.nih.gov/pubmed/22389760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/CLI.11.152
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