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Randomized Phase II Trials: Time for a New Era in Clinical Trial Design
The classic single-arm oncology phase II trial designs for evaluating an experimental regimen/agent are limited by multiple sources of bias arising from the inability to separate trial effects (such as patient selection, trial eligibility, imaging techniques and assessment schedule, and treatment lo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941394/ https://ncbi.nlm.nih.gov/pubmed/20581575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e3181e2eadf |
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