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A Review of Phase II Trial Designs for Initial Marker Validation
Phase II clinical trials aim to identify promising experimental regimens for further testing in phase III trials. In this review article, we focus on phase II designs for initial predictive biomarker validation to determine if a drug should be developed for an unselected patient population or for a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3779487/ https://ncbi.nlm.nih.gov/pubmed/23665336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2013.05.001 |
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