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All-Comers versus Enrichment Design Strategy in Phase II Trials
Designs for biomarker validation have been proposed and utilized in the Phase III oncology clinical trial setting. Broadly speaking, these designs follow either an enrichment (i.e., targeted) strategy or an all-comers (i.e., unselected) strategy. An enrichment design screens patients for the presenc...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3082391/ https://ncbi.nlm.nih.gov/pubmed/21532916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e31820e17cb |
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