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Predictive biomarker validation in practice: lessons from real trials

BACKGROUND: With the advent of targeted therapies, biomarkers provide a promising means of individualizing therapy through an integrated approach to prediction using the genetic makeup of the disease and the genotype of the patient. Biomarker validation has therefore become a central topic of discus...

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Detalhes bibliográficos
Main Authors: Mandrekar, Sumithra J, Sargent, Daniel J
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3913192/
https://ncbi.nlm.nih.gov/pubmed/20392785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774510368574
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