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Structure/function implications in a dynamic complex of the intrinsically disordered Sic1 with the Cdc4 subunit of an SCF ubiquitin ligase

Intrinsically disordered proteins can form highly dynamic complexes with partner proteins. One such dynamic complex involves the intrinsically disordered Sic1 with its partner Cdc4 in regulation of yeast cell cycle progression. Phosphorylation of six N-terminal Sic1 sites leads to equilibrium engage...

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Detalhes bibliográficos
Main Authors: Mittag, Tanja, Marsh, Joseph, Grishaev, Alexander, Orlicky, Stephen, Lin, Hong, Sicheri, Frank, Tyers, Mike, Forman-Kay, Julie D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924144/
https://ncbi.nlm.nih.gov/pubmed/20399186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.01.020
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