Regulation of the Histone Deacetylase Hst3 by Cyclin-dependent Kinases and the Ubiquitin Ligase SCF(Cdc4)

In Saccharomyces cerevisiae, histone H3 lysine 56 acetylation (H3K56ac) is a modification of new H3 molecules deposited throughout the genome during S-phase. H3K56ac is removed by the sirtuins Hst3 and Hst4 at later stages of the cell cycle. Previous studies indicated that regulated degradation of H...

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Bibliografiske detaljer
Main Authors: Delgoshaie, Neda, Tang, Xiaojing, Kanshin, Evgeny D., Williams, Elizabeth C., Rudner, Adam D., Thibault, Pierre, Tyers, Mike, Verreault, Alain
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
DNA and Chromosomes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036330/
https://ncbi.nlm.nih.gov/pubmed/24648511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.523530
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