SCF ubiquitin protein ligases and phosphorylation-dependent proteolysis.

Many key activators and inhibitors of cell division are targeted for degradation by a recently described family of E3 ubiquitin protein ligases termed Skp1-Cdc53-F-box protein (SCF) complexes. SCF complexes physically link substrate proteins to the E2 ubiquitin-conjugating enzyme Cdc34, which cataly...

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Bibliographic Details
Main Authors: Willems, A R, Goh, T, Taylor, L, Chernushevich, I, Shevchenko, A, Tyers, M
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1692661/
https://ncbi.nlm.nih.gov/pubmed/10582239
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