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SCF ubiquitin ligase targeted therapies
The recent clinical successes of inhibitors of the proteasome for the treatment of cancer have highlighted the therapeutic potential of this protein degradation system. Proteasome inhibitors prevent the degradation of numerous proteins, so increased specificity could be achieved by inhibiting the co...
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| 出版年: | Nat Rev Drug Discov |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4410837/ https://ncbi.nlm.nih.gov/pubmed/25394868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd4432 |
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