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SCF ubiquitin ligase targeted therapies
The recent clinical successes of inhibitors of the proteasome for the treatment of cancer have highlighted the therapeutic potential of this protein degradation system. Proteasome inhibitors prevent the degradation of numerous proteins, so increased specificity could be achieved by inhibiting the co...
में बचाया:
| में प्रकाशित: | Nat Rev Drug Discov |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4410837/ https://ncbi.nlm.nih.gov/pubmed/25394868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd4432 |
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