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Genetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy
Aberrant intracellular Ca(2+) regulation is believed to contribute to the development of cardiomyopathy in Duchenne muscular dystrophy. Here, we tested whether inhibition of protein kinase A (PKA) phosphorylation of ryanodine receptor type 2 (RyR2) prevents dystrophic cardiomyopathy by reducing SR C...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2919918/ https://ncbi.nlm.nih.gov/pubmed/20615971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004509107 |
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