Role of RyR2 Phosphorylation at S2814 during Heart Failure Progression

RATIONALE: Increased activity of Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is thought to promote heart failure progression. However, the importance of CaMKII phosphorylation of ryanodine receptors (RyR2) in heart failure (HF) development and associated diastolic sarcoplasmic reticulum (...

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Autors principals: Respress, Jonathan L., van Oort, Ralph J., Li, Na, Rolim, Natale, Dixit, Sayali, deAlmeida, Angela, Voigt, Niels, Lawrence, William S., Skapura, Darlene G., Skårdal, Kristine, Wisloff, Ulrik, Wieland, Thomas, Ai, Xun, Pogwizd, Steven M., Dobrev, Dobromir, Wehrens, Xander H.T.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371642/
https://ncbi.nlm.nih.gov/pubmed/22511749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.268094
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