SR calcium handling dysfunction, stress-response signaling pathways, and atrial fibrillation

Por Ai, Xun
Publicado no Front Physiol (2015)

Cardiac Electrophysiology

Por Wang, Yanggan, Du, Yimei, Ai, Xun
Publicado em 2013

Heart Failure

Por Wang, Yanggan, Yang, Yanzong, Ai, Xun
Publicado em 2014

Decreased intercellular coupling improves the function of cardiac pacemakers derived from mouse embryonic stem cells

Por Fahrenbach, John P., Ai, Xun, Banach, Kathrin
Publicado em 2008

Connexin43 knockdown or overexpression modulates cell coupling in control and failing rabbit left ventricular myocytes

Por Ai, Xun, Zhao, Weiwei, Pogwizd, Steven M.
Publicado em 2010

Enhanced activation of p21-activated kinase 1 in heart failure contributes to dephosphorylation of connexin 43

Por Ai, Xun, Jiang, Aiyang, Ke, Yunbo, Solaro, R. John, Pogwizd, Steven M.
Publicado em 2011

Bacterial protein AvrA stabilizes intestinal epithelial tight junctions via blockage of the C-Jun N-terminal kinase pathway

Por Zhang, Yongguo, Wu, Shaoping, Ma, Jun, Xia, Yinglin, Ai, Xun, Sun, Jun
Publicado no Tissue Barriers (2014)

Sex differences in repolarization and slow delayed rectifier potassium current and their regulation by sympathetic stimulation in rabbits

Por Zhu, Yujie, Ai, Xun, Oster, Robert A., Bers, Donald M., Pogwizd, Steven M.
Publicado em 2012

Novel Methods of Automated Quantification of Gap Junction Distribution and Interstitial Collagen Quantity from Animal and Human Atrial Tissue Sections

Por Yan, Jiajie, Thomson, Justin K., Wu, Xiaomin, Zhao, Weiwei, Pollard, Andrew E., Ai, Xun
Publicado em 2014

Voltage and Calcium Dual Channel Optical Mapping of Cultured HL-1 Atrial Myocyte Monolayer

Por Yan, Jiajie, Thomson, Justin K., Zhao, Weiwei, Fast, Vladimir G., Ye, Tong, Ai, Xun
Publicado no J Vis Exp (2015)

c-Jun N-terminal kinase activation contributes to reduced connexin43 and development of atrial arrhythmias

Por Yan, Jiajie, Kong, Wei, Zhang, Qiang, Beyer, Eric C., Walcott, Gregory, Fast, Vladimir G., Ai, Xun
Publicado em 2013

Arrhythmogenic effects of β(2)-adrenergic stimulation in the failing heart are due to enhanced SR Ca load

Por DeSantiago, Jaime, Ai, Xun, Islam, Mohammed, Acuna, Georgia, Ziolo, Mark T., Bers, Donald M., Pogwizd, Steven M.
Publicado em 2008

Connexin40 abnormalities and atrial fibrillation in the human heart

Por Gemel, Joanna, Levy, Andrew E., Simon, Adria R., Bennett, Katherine B., Ai, Xun, Akhter, Shahab, Beyer, Eric C.
Publicado no J Mol Cell Cardiol (2014)

TRAF3 negatively regulates platelet activation and thrombosis

Por Zhang, Rui, Zhang, Guoying, Xiang, Binggang, Chen, Xiaofeng, Tang, Lijang, Shi, Shaojun, Liu, Yani, Ai, Xun, Xie, Ping, Li, Zhenyu
Publicado no Sci Rep (2017)

Role of Stress Kinase JNK in Binge Alcohol-Evoked Atrial Arrhythmia

Por Yan, Jiajie, Thomson, Justin K., Zhao, Weiwei, Gao, Xianlong, Huang, Fei, Chen, Biyi, Liang, Qingrong, Song, Long-Sheng, Fill, Michael, Ai, Xun
Publicado no J Am Coll Cardiol (2018)

Genetic Deletion of Rnd3/RhoE Results in Mouse Heart Calcium Leakage Through Upregulation of Protein Kinase A Signaling

Por Yang, Xiangsheng, Wang, Tiannan, Lin, Xi, Yue, Xiaojing, Wang, Qiongling, Wang, Guoliang, Fu, Qin, Ai, Xun, Chiang, David Y., Miyake, Christina Y., Wehrens, Xander H.T., Chang, Jiang
Publicado no Circ Res (2014)

Transcriptional regulation of stress kinase JNK2 in pro-arrhythmic CaMKIIδ expression in the aged atrium

Por Gao, Xianlong, Wu, Xiaomin, Yan, Jiajie, Zhang, Jingqun, Zhao, Weiwei, DeMarco, Dominic, Zhang, Yongguo, Bakhos, Mamdouh, Mignery, Gregory, Sun, Jun, Li, Zhenyu, Fill, Michael, Ai, Xun
Publicado no Cardiovasc Res (2018)

Silibinin Inhibits NSCLC Metastasis by Targeting the EGFR/LOX Pathway

Por Hou, Xiaoying, Du, Hongzhi, Quan, Xingping, Shi, Lei, Zhang, Qianqian, Wu, Yao, Liu, Yang, Xiao, Jing, Li, Yong, Lu, Ligong, Ai, Xun, Zhan, Meixiao, Yuan, Shengtao, Sun, Li
Publicado no Front Pharmacol (2018)

The Stress Kinase JNK Regulates Gap Junction Cx43 Gene Expression and Promotes Atrial Fibrillation in the Aged Heart

Por Yan, Jiajie, Thomson, Justin K, Zhao, Weiwei, Wu, Xiaomin, Gao, Xianlong, DeMarco, Dominic, Kong, Wei, Tong, Min, Sun, Jun, Bakhos, Mamdouh, Fast, Vladimir G., Liang, Qingrong, Prabhu, Sumanth D, Ai, Xun
Publicado no J Mol Cell Cardiol (2017)

Stress Signaling JNK2 Crosstalk with CaMKII Underlies Enhanced Atrial Arrhythmogenesis

Por Yan, Jiajie, Zhao, Weiwei, Thomson, Justin K., Gao, Xianlong, DeMarco, Dominic M., Carrillo, Elena, Chen, Biyi, Wu, Xiaomin, Ginsburg, Kenneth S., Bakhos, Mamdouh, Bers, Donald M., Anderson, Mark E., Song, Long-Sheng, Fill, Michael, Ai, Xun
Publicado no Circ Res (2018)