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Decreased intercellular coupling improves the function of cardiac pacemakers derived from mouse embryonic stem cells

The aim of this study was to determine if embryonic stem cell-derived cardiomyocyte aggregates (ESdCs) can act as pacemakers in spontaneously active cardiomyocyte preparations when their connexin isoform expression is tuned toward a more sinus nodal phenotype. Using microelectrode array recordings (...

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Détails bibliographiques
Auteurs principaux: Fahrenbach, John P., Ai, Xun, Banach, Kathrin
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2598737/
https://ncbi.nlm.nih.gov/pubmed/18817780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2008.08.013
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