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Canonical Wnt signaling promotes pacemaker cell specification of cardiac mesodermal cells derived from mouse and human embryonic stem cells

Cardiac differentiation of embryonic stem cells (ESCs) can give rise to de novo chamber cardiomyocytes and nodal pacemaker cells. Compared with our understanding of direct differentiation toward atrial and ventricular myocytes, the mechanisms for nodal pacemaker cell commitment are not well understo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Stem Cells
Egile Nagusiak: Liang, Wenbin, Han, Pengcheng, Kim, Elizabeth H., Mak, Jordan, Zhang, Rui, Torrente, Angelo G., Goldhaber, Joshua I., Marbán, Eduardo, Cho, Hee Cheol
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7932048/
https://ncbi.nlm.nih.gov/pubmed/31648393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3106
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