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Arrhythmogenic effects of β(2)-adrenergic stimulation in the failing heart are due to enhanced SR Ca load
Ventricular tachycardia (VT) in heart failure (HF) can initiate by nonreentrant mechanisms such as delayed afterdepolarizations. In an arrhythmogenic rabbit model of HF, we have shown that isoproterenol induces VT in vivo, and aftercontractions and transient inward currents in HF myocytes. To determ...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585979/ https://ncbi.nlm.nih.gov/pubmed/18467626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.107.169011 |
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