Spontaneous Ca Waves in Ventricular Myocytes from Failing Hearts Depend on Ca(2+)-calmodulin-dependent Protein Kinase II

Increased cardiac ryanodine receptor (RyR)-dependent diastolic SR Ca leak is present in heart failure and in conditions when adrenergic tone is high. Increasing Ca leak from the SR could result in spontaneous Ca wave (SCaW) formation. SCaWs activate the inward Na/Ca exchanger (NCX) current causing a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Curran, Jerry, Brown, Kathy Hayes, Santiago, Demetrio J., Pogwizd, Steve, Bers, Donald M., Shannon, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883657/
https://ncbi.nlm.nih.gov/pubmed/20353795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.03.013
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados