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Ca(2+) spark-dependent and -independent sarcoplasmic reticulum Ca(2+) leak in normal and failing rabbit ventricular myocytes
Sarcoplasmic reticulum (SR) Ca(2+) leak is an important component of cardiac Ca(2+) signalling. Together with the SR Ca(2+)-ATPase (SERCA)-mediated Ca(2+) uptake, diastolic Ca(2+) leak determines SR Ca(2+) load and, therefore, the amplitude of Ca(2+) transients that initiate contraction. Spontaneous...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Blackwell Science Inc
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3010143/ https://ncbi.nlm.nih.gov/pubmed/20962003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.197913 |
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