Regulation of sarcoplasmic reticulum Ca(2+) leak by cytosolic Ca(2+) in rabbit ventricular myocytes

NON-TECHNICAL SUMMARY: Contraction and relaxation of the heart strongly depend on calcium (Ca(2+)) stored in the sarcoplasmic reticulum (SR). Ca(2+) stored within the SR is determined by the balance between Ca(2+) uptake and Ca(2+) leak that occurs mainly via Ca(2+) release channels, called ryanodin...

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Bibliographic Details
Main Authors: Bovo, Elisa, Mazurek, Stefan R, Blatter, Lothar A, Zima, Aleksey V
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2011
Subjects:
Cardiovascular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286684/
https://ncbi.nlm.nih.gov/pubmed/21986204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.214171
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