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Effects of cytosolic NADH/NAD(+) levels on sarcoplasmic reticulum Ca(2+) release in permeabilized rat ventricular myocytes

In the heart ischaemic conditions induce metabolic changes known to have profound effects on Ca(2+) signalling during excitation–contraction coupling. Ischaemia also affects the redox state of the cell. However, the role of cytosolic redox couples, such as the NADH/NAD(+) redox system, for the regul...

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Detalhes bibliográficos
Main Authors: Zima, Aleksey V, Copello, Julio A, Blatter, Lothar A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1664876/
https://ncbi.nlm.nih.gov/pubmed/14724208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.055848
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