Llwytho...

Mechanism of inactivation of human ribonucleotide reductase with p53R2 by gemcitabine 5′-diphosphate

Ribonucleotide reductases (RNRs) catalyze the conversion of nucleoside 5′–diphosphates to the corresponding deoxynucleotides supplying the dNTPs required for DNA replication and DNA repair. Class I RNRs require two subunits, α and β, for activity. Humans possess two β subunits: one involved in S pha...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Jun, Lohman, Gregory J. S., Stubbe, JoAnne
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917093/
https://ncbi.nlm.nih.gov/pubmed/19899807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901588z
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