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Photochemical Rescue of a Conformationally Inactivated Ribonucleotide Reductase
Class Ia ribonucleotide reductase (RNR) of Escherichia coli contains an unusually stable tyrosyl radical cofactor in the β(2) subunit (Y(122)•) necessary for nucleotide reductase activity. Upon binding the cognate α(2) subunit, loaded with nucleoside diphosphate substrate and an allosteric/activity...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6249109/ https://ncbi.nlm.nih.gov/pubmed/30347141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b07902 |
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