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Inactivation of Lactobacillus leichmannii ribonucleotide reductase by F(2)CTP: covalent modification
Ribonucleotide reductase (RNR) from Lactobacillus leichmannii, a 76 kDa monomer using adenosylcobalamin (AdoCbl) as a cofactor, catalyzes the conversion of nucleoside triphosphates to deoxynucleotides and is rapidly (<30 sec) inactivated by one equivalent (eq.) of 2′,2′-difluoro-2′-deoxycytidine...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855214/ https://ncbi.nlm.nih.gov/pubmed/20088569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902132u |
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