Downregulation of Cystine Transporter x(c)(–) by Irinotecan in Human Head and Neck Cancer FaDu Xenografts

BACKGROUND: The purpose of this study was: (1) to document the critical requirement of cystine for growth of human tumor cells in vitro, and (2) to determine the effect of the anticancer agent irinotecan on the cystine transporter x(c)(–) in head and neck FaDu xenografts. METHODS: Cell growth was me...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Chintala, Sreenivasulu, Tóth, Károly, Yin, Ming-Biao, Bhattacharya, Arup, Smith, Sylvia B., Ola, M. Shamsul, Cao, Shousong, Durrani, Farukh A., Zinia, Tanjima R., Dean, Rebecca, Slocum, Harry K., Rustum, Youcef M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: S. Karger AG 2010
विषय:
Experimental Chemotherapy
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914432/
https://ncbi.nlm.nih.gov/pubmed/20551639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000316334
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