Torthaí Cuardaigh d'Údair

1

Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases

Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases

le Rustum, Youcef M.
Foilsithe 2019

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Livro

2

Constitutive Expression of HIF-α Plays a Major Role in Generation of Clear Cell Phenotype in Human Primary and Metastatic Renal Carcinoma

Constitutive Expression of HIF-α Plays a Major Role in Generation of Clear Cell Phenotype in Human Primary and Metastatic Renal Carcinoma

le Tóth, Károly, Chintala, Sreenivasulu, Rustum, Youcef M.
Foilsithe 2014

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Artigo

3

Selenium targets resistance biomarkers enhancing efficacy while reducing toxicity of anti-cancer drugs: preclinical and clinical development

Selenium targets resistance biomarkers enhancing efficacy while reducing toxicity of anti-cancer drugs: preclinical and clinical development

le Zakharia, Yousef, Bhattacharya, Arup, Rustum, Youcef M.
Foilsithe in Oncotarget (2018)

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Artigo

4

Double Immunohistochemical Staining Method for HIF-1α and its Regulators PHD2 and PHD3 in Formalin Fixed Paraffin Embedded Tissues

Double Immunohistochemical Staining Method for HIF-1α and its Regulators PHD2 and PHD3 in Formalin Fixed Paraffin Embedded Tissues

le Vaughan, Mary M., Toth, Karoly, Chintala, Sreenivasulu, Rustum, Youcef M.
Foilsithe 2010

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Artigo

5

Non-Coding Micro RNAs and Hypoxia-Inducible Factors Are Selenium Targets for Development of a Mechanism-Based Combination Strategy in Clear-Cell Renal Cell Carcinoma—Bench-to-Bedside Therapy

Non-Coding Micro RNAs and Hypoxia-Inducible Factors Are Selenium Targets for Development of a Mechanism-Based Combination Strategy in Clear-Cell Renal Cell Carcinoma—Bench-to-Bedsi...

le Rustum, Youcef M., Chintala, Sreenivasulu, Durrani, Farukh A., Bhattacharya, Arup
Foilsithe in Int J Mol Sci (2018)

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Artigo

6

Targeting the oncogenic protein beta-catenin to enhance chemotherapy outcome against solid human cancers

Targeting the oncogenic protein beta-catenin to enhance chemotherapy outcome against solid human cancers

le Saifo, Maher S, Rempinski, Donald R, Rustum, Youcef M, Azrak, Rami G
Foilsithe 2010

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Artigo

7

Ugt1a is required for the protective effect of selenium against irinotecan-induced toxicity

Ugt1a is required for the protective effect of selenium against irinotecan-induced toxicity

le Cao, Shousong, Durrani, Farukh A., Rustum, Youcef M., Yu, Y. Eugene
Foilsithe 2012

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Artigo

8

Bevacizumab Enhances the Therapeutic Efficacy of Irinotecan against Human Head and Neck Squamous Cell Carcinoma Xenografts

Bevacizumab Enhances the Therapeutic Efficacy of Irinotecan against Human Head and Neck Squamous Cell Carcinoma Xenografts

le Cao, Shousong, Durrani, Farukh A., Toth, Karoly, Rustum, Youcef. M., Seshadri, Mukund
Foilsithe 2011

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Artigo

9

A Novel Small Molecule FL118 That Selectively Inhibits Survivin, Mcl-1, XIAP and cIAP2 in a p53-Independent Manner, Shows Superior Antitumor Activity

A Novel Small Molecule FL118 That Selectively Inhibits Survivin, Mcl-1, XIAP and cIAP2 in a p53-Independent Manner, Shows Superior Antitumor Activity

le Ling, Xiang, Cao, Shousong, Cheng, Qiuying, Keefe, James T., Rustum, Youcef M., Li, Fengzhi
Foilsithe 2012

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Artigo

10

MicroRNA-627 Mediates the Epigenetic Mechanisms of Vitamin D to Suppress Proliferation of Human Colorectal Cancer Cells and Growth of Xenograft Tumors in Mice

MicroRNA-627 Mediates the Epigenetic Mechanisms of Vitamin D to Suppress Proliferation of Human Colorectal Cancer Cells and Growth of Xenograft Tumors in Mice

le Padi, Sathish K.R., Zhang, Qunshu, Rustum, Youcef M, Morrison, Carl, Guo, Bin
Foilsithe 2013

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Artigo

11

Activity of the Vascular-Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid against Human Head and Neck Carcinoma Xenografts

Activity of the Vascular-Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid against Human Head and Neck Carcinoma Xenografts

le Seshadri, Mukund, Mazurchuk, Richard, Spernyak, Joseph A, Bhattacharya, Arup, Rustum, Youcef M, Bellnier, David A
Foilsithe 2006

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Artigo

12

Tumor Vascular Maturation and Improved Drug Delivery Induced by MethylSelenocysteine Leads to Therapeutic Synergy with Anticancer Drugs

Tumor Vascular Maturation and Improved Drug Delivery Induced by MethylSelenocysteine Leads to Therapeutic Synergy with Anticancer Drugs

le Bhattacharya, Arup, Seshadri, Mukund, Oven, Steven D, Tóth, Károly, Vaughan, Mary M, Rustum, Youcef M.
Foilsithe 2008

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Artigo

13

Augmented therapeutic efficacy of irinotecan is associated with enhanced drug accumulation

Augmented therapeutic efficacy of irinotecan is associated with enhanced drug accumulation

le Azrak, Rami G., Cao, Shousong, Durrani, Farukh A., Toth, Karloy, Bhattacharya, Arup, Rustum, Youcef M.
Foilsithe 2011

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Artigo

14

Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition

Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor...

le Chintala, Sreenivasulu, Najrana, Tanbir, Toth, Karoly, Cao, Shousong, Durrani, Farukh A, Pili, Roberto, Rustum, Youcef M
Foilsithe 2012

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Artigo

15

Hypoxia-Specific Drug Tirapazamine Does Not Abrogate Hypoxic Tumor Cells in Combination Therapy with Irinotecan and Methylselenocysteine in Well-Differentiated Human Head and Neck Squamous Cell Carcinoma A253 Xenografts

Hypoxia-Specific Drug Tirapazamine Does Not Abrogate Hypoxic Tumor Cells in Combination Therapy with Irinotecan and Methylselenocysteine in Well-Differentiated Human Head and Neck...

le Bhattacharya, Arup, Tóth, Károly, Durrani, Farukh A, Cao, Shousong, Slocum, Harry K, Chintala, Sreenivasulu, Rustum, Youcef M
Foilsithe 2008

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Artigo

16

Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1α

Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1α

le Chintala, Sreenivasulu, Tóth, Károly, Cao, Shousong, Durrani, Farukh A., Vaughan, Mary M., Jensen, Randy L., Rustum, Youcef M.
Foilsithe 2010

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Artigo

17

The mechanism of methylselenocysteine and docetaxel synergistic activity in prostate cancer cells

The mechanism of methylselenocysteine and docetaxel synergistic activity in prostate cancer cells

le Azrak, Rami G., Frank, Cheryl L., Ling, Xiang, Slocum, Harry K., Li, Fengzhi, Foster, Barbara A., Rustum, Youcef M.
Foilsithe 2006

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Artigo

18

Magnetic Resonance and Fluorescence–Protein Imaging of the Anti-angiogenic and Anti-tumor Efficacy of Selenium in an Orthotopic Model of Human Colon Cancer

Magnetic Resonance and Fluorescence–Protein Imaging of the Anti-angiogenic and Anti-tumor Efficacy of Selenium in an Orthotopic Model of Human Colon Cancer

le Bhattacharya, Arup, Turowski, Steve G, Dominguez San Martin, Ivan, Rajput, Ashwani, Rustum, Youcef M., Hoffman, Robert M., Seshadri, Mukund
Foilsithe 2011

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Artigo

19

Inhibition of Colon Cancer Growth by Methylselenocysteine - induced Angiogenic Chemomodulation is influenced by Histological Characteristics of the Tumor

Inhibition of Colon Cancer Growth by Methylselenocysteine - induced Angiogenic Chemomodulation is influenced by Histological Characteristics of the Tumor

le Bhattacharya, Arup, Tóth, Károly, Sen, Arindam, Seshadri, Mukund, Cao, Shousong, Durrani, Farukh A, Faber, Erik, Repasky, Elizabeth A., Rustum, Youcef M.
Foilsithe 2009

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Artigo

20

Generation of a Novel Transgenic Mouse Model for Bioluminescent Monitoring of Survivin Gene Activity in Vivo at Various Pathophysiological Processes : Survivin Expression Overlaps with Stem Cell Markers

Generation of a Novel Transgenic Mouse Model for Bioluminescent Monitoring of Survivin Gene Activity in Vivo at Various Pathophysiological Processes : Survivin Expression Overlaps...

le Li, Fengzhi, Cheng, Qiuying, Ling, Xiang, Stablewski, Aimee, Tang, Lei, Foster, Barbara A., Johnson, Candace S., Rustum, Youcef M., Porter, Carl W.
Foilsithe 2010

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Artigo