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Augmented therapeutic efficacy of irinotecan is associated with enhanced drug accumulation
The goal of this study is to determine whether treatment with methylselenocysteine (MSC) results in differential uptake of irinotecan and its active metabolite (SN-38) between tumors of head and neck squamous cell carcinomas and normal tissue. The in vivo synergy between MSC and irinotecan is influe...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3183362/ https://ncbi.nlm.nih.gov/pubmed/21872389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.07.023 |
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