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Triazine dendrimers as non-viral vectors for in vitro and in vivo RNAi: The effects of peripheral groups and core structure on biological activity

A family of triazine dendrimers, differing in their core flexibility, generation number, and surface functionality, was prepared and evaluated for its ability to accomplish RNAi. The dendriplexes were analyzed with respect to their physicochemical and biological properties, including condensation of...

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Detaylı Bibliyografya
Asıl Yazarlar: Merkel, Olivia M., Mintzer, Meredith A., Librizzi, Damiano, Samsonova, Olga, Dicke, Tanja, Sproat, Brian, Garn, Holger, Barth, Peter J., Simanek, Eric E., Kissel, Thomas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914146/
https://ncbi.nlm.nih.gov/pubmed/20524664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100101s
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