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Triazine dendrimers as non-viral gene delivery systems: Effects of molecular structure on biological activity

A family of generation one, two and three triazine dendrimers differing in their core flexibility was prepared and evaluated for their ability to accomplish gene transfection. Dendrimers and dendriplexes were analyzed by their physicochemical and biological properties such as condensation of DNA, si...

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Detalhes bibliográficos
Main Authors: Merkel, Olivia M., Mintzer, Meredith A., Sitterberg, Johannes, Bakowsky, Udo, Simanek, Eric E., Kissel, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773017/
https://ncbi.nlm.nih.gov/pubmed/19708683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc900243r
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