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Molecular modeling and in vivo imaging can identify successful flexible triazine dendrimer-based siRNA delivery systems
This study aimed to identify suitable siRNA delivery systems based on flexible generation 2–4 triazine dendrimers by correlating physico-chemical and biological in vitro and in vivo properties of the complexes with thermodynamic parameters calculated using molecular modeling. The siRNA binding prope...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3134114/ https://ncbi.nlm.nih.gov/pubmed/21342661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.02.016 |
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