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Polycationic triazine-based dendrimers: effect of peripheral groups on transfection efficiency

A panel of eight, second generation triazine dendrimers differing in the number of amines, guanidines, hydroxyls and aliphatic groups on the periphery was synthesized and assayed for gene transfer in an attempt to correlate the effects of surface functionality on transfection efficiency. The physico...

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Main Authors: Mintzer, Meredith A., Merkel, Olivia M., Kissel, Thomas, Simanek, Eric E.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786084/
https://ncbi.nlm.nih.gov/pubmed/19960102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b908735d
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