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Triazine dendrimers as non-viral vectors for in vitro and in vivo RNAi: The effects of peripheral groups and core structure on biological activity

A family of triazine dendrimers, differing in their core flexibility, generation number, and surface functionality, was prepared and evaluated for its ability to accomplish RNAi. The dendriplexes were analyzed with respect to their physicochemical and biological properties, including condensation of...

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Bibliografski detalji
Glavni autori: Merkel, Olivia M., Mintzer, Meredith A., Librizzi, Damiano, Samsonova, Olga, Dicke, Tanja, Sproat, Brian, Garn, Holger, Barth, Peter J., Simanek, Eric E., Kissel, Thomas
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914146/
https://ncbi.nlm.nih.gov/pubmed/20524664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp100101s
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