Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces

APOBEC3G is a DNA cytidine deaminase that has anti-viral activity against HIV-1 and other pathogenic viruses. In this study the crystal structure of the catalytically active C-terminal domain was determined to 2.25 Å. This structure corroborates features previously observed in NMR studies, a bulge i...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Shandilya, Shivender M. D., Nalam, Madhavi N. L., Nalivaika, Ellen A., Gross, Phillip J., Valesano, John C., Shindo, Keisuke, Li, Ming, Munson, Mary, Harjes, Elena, Kouno, Takahide, Matsuo, Hiroshi, Harris, Reuben S., Somasundaran, Mohan, Schiffer, Celia A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913127/
https://ncbi.nlm.nih.gov/pubmed/20152150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.10.016
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky