Chargement en cours...
A computational analysis of the structural determinants of APOBEC3's catalytic activity and vulnerability to HIV-1 Vif
APOBEC3s (A3) are Zn(2+) dependent cytidine deaminases with diverse biological functions and implications for cancer and immunity. Four of the seven human A3s restrict HIV by 'hypermutating' the reverse-transcribed viral genomic DNA. HIV Virion Infectivity Factor (Vif) counters this restri...
Enregistré dans:
| Publié dans: | Virology |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4857191/ https://ncbi.nlm.nih.gov/pubmed/25461536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.09.023 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|