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Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G
The human APOBEC3G (A3G) DNA cytosine deaminase restricts and hypermutates DNA-based parasites including HIV-1. The viral infectivity factor (Vif) prevents restriction by triggering A3G degradation. While the structure of the A3G catalytic domain is known, the structure of the N-terminal Vif-binding...
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| 出版年: | Nat Struct Mol Biol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456288/ https://ncbi.nlm.nih.gov/pubmed/25984970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3033 |
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