Crystal structure of the DNA cytosine deaminase APOBEC3F: the catalytically active and HIV-1 Vif-binding domain

Human APOBEC3F is an anti-retroviral single strand DNA cytosine deaminase, susceptible to degradation by the HIV-1 protein Vif. In this study the crystal structure of the HIV Vif binding, catalytically active, C-terminal domain of APOBEC3F (A3F-CTD) was determined. The A3F-CTD shares structural moti...

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Detalhes bibliográficos
Main Authors: Bohn, Markus-Frederik, Shandilya, Shivender M. D., Albin, John S., Kouno, Takahide, Anderson, Brett D., McDougle, Rebecca M., Carpenter, Michael A., Rathore, Anurag, Evans, Leah, Davis, Ahkillah N., Zhang, Jing Ying, Lu, Yongjian, Somasundaran, Mohan, Matsuo, Hiroshi, Harris, Reuben S., Schiffer, Celia A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805256/
https://ncbi.nlm.nih.gov/pubmed/23685212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.04.010
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