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Mass Spectrometry analysis of HIV-1 Vif reveals an increase in ordered structure upon oligomerization in regions necessary for viral infectivity

HIV-1 Vif, an accessory protein in the viral genome, performs an important role in viral pathogenesis by facilitating the degradation of APOBEC3G, an endogenous cellular inhibitor of HIV-1 replication. In this study, intrinsically disordered regions are predicted in HIV-1 Vif using sequence based al...

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Detalhes bibliográficos
Principais autores: Auclair, Jared R., Green, Karin M., Shandilya, Shivender, Evans, James E., Somasundaran, Mohan, Schiffer, Celia A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366188/
https://ncbi.nlm.nih.gov/pubmed/17598142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.21471
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