APOBEC3F Determinants of HIV-1 Vif Sensitivity

HIV-1 Vif counteracts restrictive APOBEC3 proteins by targeting them for proteasomal degradation. To determine the regions mediating sensitivity to Vif, we compared human APOBEC3F, which is HIV-1 Vif sensitive, with rhesus APOBEC3F, which is HIV-1 Vif resistant. Rhesus-human APOBEC3F chimeras and am...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Land, Allison M., Shaban, Nadine M., Evans, Leah, Hultquist, Judd F., Albin, John S., Harris, Reuben S.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248952/
https://ncbi.nlm.nih.gov/pubmed/25142588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02362-14
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