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Long-Term Restriction by APOBEC3F Selects Human Immunodeficiency Virus Type 1 Variants with Restored Vif Function

Tandem stop mutations K26X and H27X in human immunodeficiency virus type 1 (HIV-1) vif compromise virus replication in human T-cell lines that stably express APOBEC3F (A3F) or APOBEC3G (A3G). We previously reported that partial resistance to A3G could develop in these Vif-deficient viruses through a...

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Detalhes bibliográficos
Main Authors: Albin, John S., Haché, Guylaine, Hultquist, Judd F., Brown, William L., Harris, Reuben S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937771/
https://ncbi.nlm.nih.gov/pubmed/20686027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00632-10
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