A carregar...

Vif Proteins of Human and Simian Immunodeficiency Viruses Require Cellular CBFβ To Degrade APOBEC3 Restriction Factors

HIV-1 requires the cellular transcription factor CBFβ to stabilize its accessory protein Vif and promote APOBEC3G degradation. Here, we demonstrate that both isoforms of CBFβ allow for increased steady-state levels of Vif, enhanced APOBEC3G degradation, and increased viral infectivity. This conserve...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Hultquist, Judd F., Binka, Mawuena, LaRue, Rebecca S., Simon, Viviana, Harris, Reuben S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302251/
https://ncbi.nlm.nih.gov/pubmed/22205746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06950-11
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!