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The Activity Spectrum of Vif from Multiple HIV-1 Subtypes against APOBEC3G, APOBEC3F, and APOBEC3H

The APOBEC3 family comprises seven cytidine deaminases (APOBEC3A [A3A] to A3H), which are expressed to various degrees in HIV-1 susceptible cells. The HIV-1 Vif protein counteracts APOBEC3 restriction by mediating its degradation by the proteasome. We hypothesized that Vif proteins from various HIV-...

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Detalhes bibliográficos
Main Authors: Binka, Mawuena, Ooms, Marcel, Steward, Myeika, Simon, Viviana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255910/
https://ncbi.nlm.nih.gov/pubmed/22013041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06082-11
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