Vif hijacks CBF – β to degrade APOBEC3G and promote HIV–1 infection

Restriction factors, such as the retroviral complementary DNA deaminase APOBEC3G, are cellular proteins that dominantly block virus replication(1-3). The AIDS virus, human immunodeficiency virus type 1 (HIV-1), produces the accessory factor Vif, which counteracts the host’s antiviral defence by hija...

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Bibliographische Detailangaben
Hauptverfasser: Jäger, Stefanie, Kim, Dong Young, Hultquist, Judd F., Shindo, Keisuke, LaRue, Rebecca S., Kwon, Eunju, Li, Ming, Anderson, Brett D., Yen, Linda, Stanley, David, Mahon, Cathal, Kane, Joshua, Franks-Skiba, Kathy, Cimermancic, Peter, Burlingame, Alma, Sali, Andrej, Craik, Charles S., Harris, Reuben S., Gross, John D., Krogan, Nevan J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310910/
https://ncbi.nlm.nih.gov/pubmed/22190037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10693
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